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Madelyn fought cancer from the age of 2 until she
passed into the hands of Jesus at the age of 6. Through it all she smiled, laughed and showed the world what it meant to be
a real princess. Here is a glimpse into her journey; to learn more about her or her fight, please visit her website.January 2, 2004-We
began our journey with symptoms of pain in the left leg and a slight limp just after turning two. Dr. visits
and tests follow. January 29, 2004-We received a call from Vanderbilt Medical in Nashville, Madelyn has a mass in the
abdomen, believed to be Neuroblastoma. We arrive at St Jude that afternoon. January 30, 2004-Madelyn had a bone
marrow aspirate. Our worst fears were confirmed. Madelyn has STAGE IV NEUROBLASTOMA. 80 percent of her bone marrow
is covered. Her primary doctor is Dr Wayne Furman February 2, 2004-Madelyn has surgery to place her central line.
She starts chemo later that night. Protocol consist of Cyclophosphamide/Cytoxin, Doxorubicin/Adrimycin, Etoposide/VP16 &
Cisplatin. March 16, 2004-Madelyn has an incomplete resection of her primary tumor along with the right adrenal gland
by Dr. Davidoff. June 2004-Madelyn needs additional chemo beyond protocol, Topotecan. September 20, 2004-Madelyn
receives her stem-cell transplant on the CD-133 protocol consisting of Mephalan & Busulfan September 29, 2004-Madelyn
is sent to ICU and put on a ventilator for 8 days due to mucussitus, a complication from the Mephalan. November 2, 2004-Test
results show Madelyn's transplant was not successful. November 20, 2004-Again, back in ICU on a ventalator for 9
days possibly due to more complications of BMT chemo and low T-cells. December 2004-Madelyn was put on a Phase 1 Study,
Irrinotecan/Temozolomide. January 2005-Madelyn has two rounds of Accutane
while having the time of her life on her MAKE A WISH trip to DISNEY WORLD! Her dream come true was to meet Snow White but
then got to meet them all! March 2005-Madelyn received 15 rounds of radiation treatments. July 2005-Test shows less
than one percent in the bone marrow! She starts ICE chemotherapy in combination with Irrinotecan & Temozolomide. Sept
2005-Tests show ZERO in the bone marrow! MIBG lights up only the primary and bones around the left eye. Dec 2005-tests
show little activity in bone marrow, primary and eye. Madelyn is the first at St Jude to start a Phase 2 anti-body study:
hu14:18IL-2. January 2006-Madelyn completes round 2 of anti-body. She is put
on a vent for the third time for 13 days due to fluid buildup and miraculously recovers! March 2006 to October 2006-Maddie
gets scans every 3 months that shows STABLE tumor in the abdomen and ZERO in the bone marrow! January 25, 2007-Maddie's scans show she has RELAPSED/PROGRESSED with four new spots in the left leg and
three in her head. February 1, 2007-Chemo consisting of Cyclophosphamide & Etoposide/VP-16 starts. February
14 2007-Maddie begins to lose her hair again. June 2007-Maddie is the first at St Jude to start TEMKID, an IV chemotherapy
once a week. She gets 8 rounds. August 2007-Maddie has low T-cells from the TEMKID and gets a virus called ParainfluenzaIII
and is placed in ICU on a vent for 13 days. November 2007-after 14 weeks of no treatment due to waiting on a study to
open and time to heal, a MIBG and CT show Maddie's tumor has progressed with one new spot on the right hip and one in
the back of her head has grown inward toward the brain. She has pain in left leg and head. Nov 20, 2007-2 days before
Thanksgiving radiation begins and then 5 days the week after. December 17-(her birthday-we receive news that MIBG lights
up all over and her bone marrow is covered 80 percent. December 18, 2007-we spend 5 hours in a clinic room making the toughest
decision of our life-treatment is no longer an option, we are keeping our faith and trust in our Lord Jesus Christ-she is
given "weeks not months" February 2, 2008 at 3:19am-While holding her mommy
and daddy's hand Madelyn twirled her way to Jesus.
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| Maddie's Caringbridge Site |
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| St Jude patient of the month-Oct 2007 |
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